caspases相关论文
Cytosolic nucleic acid sensors are critical for sensing nucleic acids and initiating innate immunity during microbial in......
目的:观察藤龙补中汤(TLBZT)对CT26大肠癌肿瘤生长和细胞凋亡的作用。方法:BALB/c小鼠皮下注射CT26细胞,待肿瘤组织长至可测量范围时......
Realgar-lnduced Apoptosis of Cervical Cancer Cell Line Siha via Cytochrome C Release and Caspase-3 a
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Radiosensitization of Head and Neck Squamous Cell Carcinoma by a SMAC-Mimetic Compound, SM-164, Requ
Chemoradiation is the treatment of choice for locally advanced head and neck squamous cell carcinoma (HNSCC).However, ra......
目的:不同浓度氟化钠(NaF)对H9c2心肌细胞进行染毒培养,细胞色素C释放和caspase家族的表达在氟化物诱导心肌细胞凋亡中的意义方法:H9c......
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目的 探究死亡受体途径、线粒体途径与氟诱导肾脏细胞凋亡的关系.方法 48只SD大鼠随机分为4组:对照组、低氟组、中氟组和高氟组,每......
Attenuation of Scutellaria barbata flavonoids on cortical cytoplasm apoptotic factors disorders indu
OBJECTIVE To investigate the effect of SBF on cortical cytoplasm apoptotic factors disturbances induced by complex Aβ25......
H2O2 INDUCES APOPTOSIS OF RABBIT CHONDROCYTES VIA BOTH THE EXTRINSIC AND THE CASPASE-INDEPENDENT INT
Osteoarthritis (OA), one of the most common joint diseases with unknown etiology, is characterized by the progressive de......
一氧化氮(NO)可以诱导多种细胞产生凋亡,但其机制尚未阐明。近年来的研究发现,NO诱导细胞凋亡过程中,抑癌基因p53表达增加、原癌基因Bcl......
Phenylethanoid glycosides from Cistanche tubulosa inhibits the growth of B16-F10 cells both in vitro
Ethnopharmacological relevance: Cistanche has been used as traditional Chinese medicine for several thousands of yea......
细胞凋亡是畜禽被屠宰后细胞必须经历的过程,也是细胞自我破坏的程序性死亡过程。半胱氨酸蛋白酶(Caspases)作为一种IL-1β转化蛋......
Objective To investigate the apoptosis-inducing effect of endogenous nitric oxide (NO) suppression in gastric cancer cel......
Grape seed proanthocyanidin extract induced mitochondria-associated apoptosis in human acute myeloid
The important aim in cancer treatment is the selective killing of cancer cells without damaging healthy cells and the mo......
目的 探讨NDGA诱导胃癌细胞凋亡的分子机制。方法 分光光度法检测caspase 3的细胞活性 ,同时用Westernblot分析caspase 3及其底......
目前 ,以 DNA拓扑异构酶为靶点的抗癌药已成为临床有效的抗肿瘤一线药物 ,随着此类药物越来越多地被开发 ,其作用机制的研究受到广......
Mesua ferrea stem bark extract induces apoptosis and inhibits metastasis in human colorectal carcino
Considering the great potential of natural products as anticancer agents, the present study was designed to explore the ......
Growth Inhibition and Apoptosis Inducing Mechanisms of Curcumin on Human Ovarian Cancer Cell Line A2
Objective: To explore the growth inhibition effects and apoptosis inducing mechanisms of curcumin on human ovarian cance......
Caspases, a family of cysteine proteases, mediate programmed cell death during early neural development and neurodegener......
Anti-proliferative and apoptotic effects of S1, a tetrandrine derivative, in human gastric cancer BG
The aim of the study was to investigate the anti-proliferation and apoptosis-inducing effects of S1, a novel tetrandrine......
目的研究细胞因子IFN-γ和TNF-α对小鼠胰岛瘤细胞株MIN6中caspase-3活化的影响。方法用IFN-γ、TNF-α单独或联合刺激MIN6细胞后,......
目的以动脉粥样硬化(As)病灶中的主要细胞类型—血管平滑肌细胞为模型,对比研究同型半胱氨酸(Hcy)和半胱氨酸(Cys)在致As发病效应......
JTE-522-induced apoptosis in human gastric adenocarinoma cell line AGS cells by caspase activation a
AIM:To investigate the role of the mitochondrial pathway inJTE-522-induced apoptosis and to investigate therelationship......
目的:研究caspases家族成员在二乙酰二脱水卫矛醇(DADAG)诱导人白血病HL-60细胞凋亡中的作用.方法:MTT法观察DADAG的体外抗增殖作......
目的:研究抗抑郁药地昔帕明(Des)对胶质瘤C6细胞的凋亡诱导作用以及对凋亡关键效应分子caspase3和凋亡早期信号[Ca~(2+)]_i的调控......
目的 探讨As2 O3 对人食管鳞癌细胞的效应及其作用机制。方法 用细胞学、生物化学和DNA微阵列技术分析人食管鳞癌细胞经As2 O3 ......
Peroxisome proliferator-activated receptor gamma ligands inhibit cell growth and induce apoptosis in
AIM:To investigate the characteristics of PPAR gammaligands induced apoptosis in liver cancer cells.METHODS:The effects......
目的 通过对脑膜瘤组织中凋亡程度以及脑膜瘤组织中凋亡相关基因的蛋白表达进行研究 ,探讨不同病理分级脑膜瘤中凋亡强弱程度以及......
细胞凋亡抑制是淋巴瘤的发生机制之一,拮抗Fas凋亡途径是大部分B细胞非霍奇金淋巴瘤(B-NHL)的共同特征,构成该类肿瘤发生的重要原......
细胞凋亡 (Apoptosis)是机体的一种主动、程序化生理过程 ,受体内多种因素调节 ,凋亡过程的紊乱与肿瘤的发生发展密切相关。有研究......
细胞死亡是许多临床状态下的一种重要现象 ,具有广泛的病理学意义。细胞凋亡 (apoptosis)是细胞死亡的另一种方式 ,又称程序性细胞......
Allitridi induces apoptosis by affecting Bcl-2 expression and caspase-3 activity in human gastric ca
AIM: To investigate the mechanism of allitridi-induced apoptosis in human gastric cancer cell line BGC823. METHODS: Gro......
目的 :研究围手术期异体输血对胃癌患者Th细胞极化的影响。方法 :胃癌根治手术患者 ,接受围手术期异体输血。用流式细胞术检测TH细......
环氧合酶-2(cyclooxygenase-2,COX-2)在多种肿瘤中呈过表达状态,正成为肿瘤靶向治疗的焦点.特异性COX-2抑制剂塞来昔布引起的不良......
细胞凋亡调控因子包括诱导因子(如Caspases家族、Fas/FasL、P53等)和抑制因子(如Bcl-2、IAP家族、Clusterin等),它们与前列腺癌的......
Apoptosis, also known as programmed cell death,is a normal process contributing to tissue tumor during development and ......
[目的]建立大鼠椎间盘软骨终板细胞凋亡体外模型.[方法]为了模拟椎间盘内部低营养低代谢环境,采用低胎牛血清培养法培养椎间盘软骨......
<正>近年来随着人民生活水平的大幅提高,我国缺血性心脑血管疾病(ischemic cerebrovascular disease,ICCVD)列居各种疾病死因的第一......
Celastrol induces caspase-dependent apoptosis of hepatocellular carcinoma cells by suppression of ma
OBJECTIVE: To investigate the efficacy of celastrol treatment of hepatocellular carcinoma(HCC) cells in vitro and in viv......
胰岛素-胰高血糖素瘤克隆20( IG20)在人类细胞中至少可表达6种剪接异型体,这些蛋白主要通过细胞肿瘤坏死因子(TNF)与TNF相关死亡配......
Effect of Shenfu Injection (ginesenoside and aconite alkaloid) on the apoptosis of intestinal mucosa
Objective: To investigate the effect of Shenfu Injection (SF, ginesenoside and aconite alkaloid) on the apoptosis of int......
为研究低氧胁迫对大口黑鲈“优鲈3号”呼吸代谢和细胞凋亡的影响,在溶解氧(DO)为(0.70±0.05)mg/L的条件下,测定了试验鱼肝脏及脑......
当细胞以异常的模式进行复制的时候,机体会释放一系列的死亡信号激发细胞自我摧毁,以免异常的细胞变成癌细胞。关于这一细胞凋亡......
CYLD deletion triggers nuclear factor-κB-signaling and increases cell death resistance in murine hep
AIM:To analyze the role of CYLD for receptor-mediated cell death of murine hepatocytes in acute liver injury models.METH......